Secondary bronchiolitis obliterans organising pneumonia in a patient with carbamazepine-induced hypogammaglobulinemia
- Division of Infectious and Respiratory Diseases, Department of Internal Medicine, Tohoku University Hospital, Sendai, Japan
- Correspondence to:
Tsutomu Tamada
Division of Infectious and Respiratory Diseases, Department of Internal Medicine, Tohoku University Hospital, Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan; tamada{at}rid.med.tohoku.ac.jp
A 49-year-old woman had been treated with carbamazepine for 2 years because of epilepsy. She was referred to us for progressive exertional dyspnea and prolonged productive cough. Chest computed tomography (CT) scan showed bilateral infiltrates including ground glass opacities and consolidations predominantly in the lower lung fields. Her laboratory findings showed severe hypogammaglobulinemia, that is, immunoglobulin (Ig) G 418 mg/dl (normal, 748–1694 mg/dl), Ig A 20 mg/dl (91–391 mg/dl) and Ig M 51 mg/dl (33–254 mg/dl). Carbamazepine and other suspected antibiotics were all …
