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Case Report
Tubular aggregate myopathy presenting with acute type II respiratory failure and severe orthopnoea
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  1. N Shahrizaila1,
  2. W S Lim2,
  3. D K Robson3,
  4. W J Kinnear4,
  5. A J Wills1
  1. 1Department of Neurology, Queen’s Medical Centre, Nottingham, UK
  2. 2Department of Respiratory Medicine, Nottingham City Hospital, Nottingham, UK
  3. 3Department of Histopathology, Queen’s Medical Centre, Nottingham, UK
  4. 4Department of Respiratory Medicine, Queen’s Medical Centre, Nottingham, UK
  1. Correspondence to:
    Dr N Shahrizaila
    Department of Neurology, Queen’s Medical Centre, Nottingham NG7 1UH, UK; tshahrizaila{at}hotmail.com

Abstract

Acute hypercapnic respiratory failure (AHRF) is a common reason for hospital admission. Most patients have an underlying chronic lung disease such as chronic obstructive pulmonary disease. We report the case of a man who presented with AHRF secondary to tubular aggregate myopathy.

  • AHRF, acute hypercapnic respiratory failure
  • COPD, chronic obstructive pulmonary disease
  • FEV1, forced expiratory volume in 1 second
  • FVC, forced vital capacity
  • NIV, non-invasive ventilation
  • tubular aggregates
  • myopathy
  • diaphragm paralysis
  • hypercapnic respiratory failure

https://doi.org/10.1136/thx.2004.028233

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    Footnotes

    • Competing interests: none declared.