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Thorax 60:723-729 doi:10.1136/thx.2004.039115
  • Chronic obstructive pulmonary disease

Patterns of dynamic hyperinflation during exercise and recovery in patients with severe chronic obstructive pulmonary disease

Table 2

 Mean (SE) peak exercise data of the study population and subgroups

COPD(n = 20) Early hyperinflators(n = 12) Late hyperinflators(n = 8)
Wpeak, peak workload; V˙o2, oxygen uptake; RER, respiratory exchange ratio; fc, cardiac frequency; V˙e, minute ventilation; fb, breathing frequency; EIVcw, end inspiratory chest wall volume; EEVcw, end expiratory chest wall volume; IC, inspiratory capacity; OEP, optoelectronic plethysmography; IRVcw, inspiratory reserve chest wall volume; Vt, tidal volume; TLCVcw, chest wall volume at total lung capacity.
Δ indicates changes from quiet breathing.
*Significant differences between groups.
Wpeak (Watt) 45 (4) 44 (7) 47 (5)
Wpeak (% pred) 37 (3) 34 (4) 40 (5)
Exercise tolerance (min) 6.7 (0.4) 6.4 (0.5) 7.2 (0.6)
o2 (l/min) 0.83 (0.06) 0.81 (0.09) 0.84 (0.08)
o2 (% pred) 50 (4) 47 (5) 53 (7)
RER 1.06 (0.05) 1.08 (0.02) 1.07 (0.07)
fc (beats/min) 115 (2) 114 (4) 116 (5)
fc (% pred) 73 (2) 72 (2) 75 (5)
Spo2 (%) 92 (1) 93 (2) 91 (1)
e (l/min) 30.8 (2.0) 31.1 (2.6) 30.1 (2.7)
Vt (l) 1.24 (0.08) 1.22 (0.10) 1.28 (0.12)
fb (breaths/min) 26 (2) 26 (3) 25 (2)
Dyspnoea (Borg) 4.1 (0.3) 4.1 (0.5) 3.6 (0.3)
Leg fatigue (Borg) 4.1 (0.3) 4.3 (0.3) 3.4 (0.7)
ΔEIVcw (l) 0.97 (0.10) 1.17 (0.17) 0.66 (0.08)*
ΔEEVcw (l) 0.53 (0.09) 0.75 (0.09) 0.21 (0.08)*
VtOEP/ICOEP (%) 86 (2) 88 (2) 83 (6)
IRVcw (l) 0.19 (0.04) 0.14 (0.05) 0.26 (0.08)
IRVcw/TLCVcw (%) 7 (1) 7 (1) 7 (3)

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