N-Acetylcysteine and disease progression in COPD
- K Satkunam
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Specialist Registrar, Newham University Hospital, London, UK; karnan@doctors.org.uk
▴ Decramer M, Rutten-van Mölken M, Dekhuijzen PR, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility
Study, BRONCUS): a randomized placebo-controlled trial. Lancet2005;365:1552–60
It is known that oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). In this study the anti-oxidant N-acetylcysteine (NAC) was used to assess whether this drug could …