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Lymphatic vessels as targets for intervention in the treatment of inflammatory airway diseases
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  1. J Quint
  1. Specialist Registrar in Respiratory Medicine, Southend Hospital, Southend, UK; jenni_quint@hotmail.com

https://doi.org/10.1136/thx.2005.la0155

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    ▴ Baluk P, Tammela T, Ator E, et al. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest2005;115:247–57
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    This collaborative group investigated the factors triggering lymphangiogenesis in response to increased leakage in airway inflammation. They used mouse models with chronic respiratory tract infections with Mycoplasma pulmonis and models with adenoviral transduction of airway epithelium with VEGF family growth factors.

    In pathogen free mice, blood and lymphatic …

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