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Thorax 2005;60:225 doi:10.1136/thx.2004.la0136
  • Miscellaneous

Intravenous immunoglobulin improves clinical outcome in Churg-Strauss syndrome

  1. A Padmanabhan
  1. Consultant Respiratory Physician, S P Fort Hospital, Trivandrum, India; arjun_p@vsnl.com

    ▴ Danieli MG, Cappelli M, Malcangi G, et al. Long term effectiveness of intravenous immunoglobulin in Churg-Strauss syndrome. Ann Rheum Dis2004;63:1649–54

    Churg-Strauss Syndrome (CSS) is a necrotising vasculitis of medium and small sized vessels clinically characterised by asthma, eosinophilia, and systemic vasculitis associated with circulating antibodies to antineutrophil cytoplasmic antigen (ANCA). The standard treatment of this condition comprises corticosteroids and, in severe cases, cytotoxic drugs. However, this treatment protocol is associated with a high relapse rate and significant drug …

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