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Correlation between carbon dioxide retention during exercise and the rate of decline of FEV1 in cystic fibrosis
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Progressive decline in lung function is an important cause of morbidity and mortality in patients with cystic fibrosis (CF). Markers to identify the patients at risk of rapid decline in their clinical condition are lacking. No study to date has used carbon dioxide (CO2) retention during exercise to predict the rate of decline in respiratory function in CF. …