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Thorax 59:428-433 doi:10.1136/thx.2003.008912
  • Lung cancer

Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma

Table 4

Multivariate Cox regression analysis of overall survival in patients with malignant mesothelioma

Hazard ratio (95% CI) p value
COX-2
    0–4 0.143 (0.032 to 0.646) 0.011
    >4 1
p21
    <10% 2.191 (0.685 to 7.005) 0.186 (NS)
    >10% 1
p27
    <10% 4.016 (0.913 to 17.653) 0.066 (NS)
    >10% 1

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