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FENO as a diagnostic tool in paediatric asthma
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Malmberg and colleagues reported the robust discriminatory properties of exhaled nitric oxide (FENO) for asthma in a paediatric population, but also noted that 29% of the subjects studied could not perform the manoeuvres necessary for online NO measurements at a target expiratory flow rate of 50 ml/s.1 These results are consistent with those reported by Canady and colleagues who noted that 24% of children studied could not perform online NO analysis.2 We studied healthy and asthmatic adults and found a similarly robust ability of NO …