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Thorax 2004;59:999
  • Miscellaneous

Sildenafil and exercise capacity in hypoxic pulmonary hypertension

  1. M M Mughal
  1. The Cleveland Clinic Foundation, Cleveland, Ohio, USA; mughalm@ccf.org

    ▴ Ghofrani HA, Reichenberger F, Kohstall MG, et al. Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp. Ann Intern Med2004;141:169–77

    This study examined the influence of oral sildenafil on pulmonary haemodynamics and exercise tolerance during hypoxia induced pulmonary hypertension in healthy mountaineers and trekkers who were not susceptible to high altitude pulmonary oedema. Fourteen healthy volunteers (12 men, …

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