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Sensitivity of pulmonary function tests in assessing whether bronchodilatation is different in healthy subjects and asthmatics
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The ability of different pulmonary function tests to detect dose-response effects depends on both the variability and sensitivity of the methods used. In clinical trials bronchodilatation is usually assessed by spirometry. Body plethysmography and impulse oscillation (IOS) are alternative techniques. The advantage of IOS is that it is simpler to perform and requires minimal effort from …