Multidrug resistant tuberculosis following lung transplantation: treatment with pulmonary resection
- 1Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
- 2Department of Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
- Correspondence to:
Dr M R Kramer
Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva 49 100, Israel; kramermnetvision.net.il
- Received 23 December 2002
- Accepted 26 March 2003
Abstract
Recipients of organ transplants are at increased risk for infection owing to their immunosuppressed state and the possibility of contamination of the donor organ. We report a case of multidrug resistant tuberculosis (MDR) transmission via a donor lung. After medical treatment with four drugs had failed, the patient underwent right upper lobectomy. There were no signs of disease on follow up more than 2 years later. To our knowledge, this is the first report of MDR tuberculosis in a lung transplant recipient. The need for a non-conservative approach, including pulmonary resection, to eradicate the infection is emphasised.
