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Thorax 59:11-15
  • Asthma

Early prescriptions of antibiotics and the risk of allergic disease in adults: a cohort study

Table 5

Summary of other studies of early antibiotic prescription and allergic disease

Author (ref) Country Age (years) N Age of prescription (years) No of prescriptions Adjusted risk estimate
Atopy Asthma Hay fever Eczema
NR = not reported.
Farooqi4 UK 14–23 1934 <2 1+ v 0 NR 3.19 2.04 2.04
Alm5 Sweden 5–13 675 Ever 1+ v 0 1.24 NR NR NR
Von Mutius6 Germany 5–11 6174 <1 1–2 v 0 0.96 1.64 1.12 1.26
Wickens7 New Zealand 5–10 456 Ever 1+ v 0 NR 2.74 1.99 1.23
Droste8 Belgium 7–8 1206 (675) <1 1+ v 0 1.1 1.7 2.3 1.3
Illi9 Germany 7 1314 Ever 2+ v 0/1 “No effect” 1.08 NR NR
McKeever10 UK 0–11 29238 <1 5+ v 0 NR 1.99 1.14 1.01
This study UK 19–46 746 <5 1+ v 0 1.16 1.84 1.24 NR

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