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Thorax 58:ii29-ii38 doi:10.1136/thorax.58.suppl_2.ii29
  • BTS GUIDELINES

BTS guidelines for the management of malignant pleural effusions

Table 3

Sclerosing agents available in UK

Sclerosing agent Recommended dose Average success rate Common side effects Serious complications Approx cost per treatment Manufactured in UK No of treatments
ARDS=adult respiratory distress syndrome.
*Produced in Germany and available via international wholesalers.
†Produced under manufacturer’s licence in UK.
‡Not available or licensed for use in the UK.
Tetracycline 1–1.5 g 65%49,53–55 Chest pain,
fever, cough 		None 1.5 g: £13.95† No 1
Sterile talc
(slurry or poudrage) 		2–5 g 90%42,64,65,68 Chest pain,
fever 		Respiratory failure/ARDS 5 g: £1.60 Yes* 1
Bleomycin 60 units 61%56,67,72–74 Chest pain,
fever, nausea 		None 60 units: £68.75 Yes 1
Doxycycline 500 mg 76%43,47,78,79 Chest pain,
fever 		None 500 mg: £29.50 No‡ >1

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