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Thorax 58:654-658 doi:10.1136/thorax.58.8.654
  • Chronic obstructive pulmonary disease

Prednisolone response in patients with chronic obstructive pulmonary disease: results from the ISOLDE study

Table 5

Relationship between number of exacerbations per year and prednisolone response using the Callahan and ATS definitions

Fluticasone propionate Placebo % reduction (95% CI)
n Mean* n Mean*
*Mean number of exacerbations per year from Poisson model.
Callahan responder 29 0.85 33 1.90 55% (25 to 74)
Callahan non-responder 232 1.32 229 1.55 15% (0 to 28)
ATS responder 37 1.10 37 1.68 35% (0 to 58)
ATS non-responder 224 1.39 225 1.57 17% (2 to 30)

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