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LUNG ALERT
A new test for latent tuberculosis infection?
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  1. K Dheda
  1. University College, London, UK, k.dheda@ucl.ac.uk

https://doi.org/10.1136/thorax.58.8.653

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    ▴ Ewer K, Deeks J, Alvarez L, et al. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet2003;361:1168–73
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    This study compared the enzyme linked immunospot assay (ELISPOT) with tuberculin skin testing (TST) for the diagnosis of latent tuberculosis infection (LTBI) in low prevalence settings. The ELISPOT assay measures interferon gamma secretion by blood mononuclear cells to ESAT-6, an antigen present in Mycobacterium tuberculosis but not …

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