Table 1
Expression of growth factor receptors in malignant mesothelioma cells
| ZL34 | SPC212 | M28K | M38K | STAV-FCS | ZL5 | |
|---|---|---|---|---|---|---|
| Expression of growth factor receptors was performed using RT-PCR; + indicates PCR product detected, – indicates no PCR product detected. | ||||||
| Positive controls: for EGFR, U-1080; for c-erbB2, B3, B4 and IGF-IR, MCF-7; for PDGFR-β, M14k; for IGF-IIR, chang; for c-kit, NCI H69; for FGFR-1, -2, -3 and -4, T-47D. Negative controls: no template added. | ||||||
| *HGF receptor.17 | ||||||
| †SCF receptor. | ||||||
| EGFR | + | + | + | + | + | + |
| c-erbB2 | – | – | – | – | – | – |
| c-erbB3 | – | – | – | – | – | – |
| c-erbB4 | + | + | + | + | + | – |
| c-met* | + | + | + | + | + | + |
| PDGFR-β | + | – | + | + | + | + |
| IGF-IR | + | + | + | + | + | + |
| IGF-IIR | + | + | + | + | + | + |
| c-kit† | + | + | + | + | + | + |
| FGFR-1 | – | + | + | + | – | + |
| FGFR-2 | – | – | – | – | + | – |
| FGFR-3 | + | + | + | + | + | – |
| FGFR-4 | + | + | + | + | + | + |
