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Thorax 58:1066-1070 doi:10.1136/thorax.58.12.1066
  • Cough

Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis

Table 3

Bronchial biopsy subepithelial cell counts per mm2

Normal (n = 9) Idiopathic cough (n = 10) Explained cough (n = 13)
Data are expressed as median (range).
*p<0.05 (Kruskal-Wallis test).
CD3 (T cells) 38 (8–69) 22 (6–105) 57 (19–125)
CD4 12 (0–51) 27 (4–119) 33 (12–95)
CD8 16 (0–33) 9 (1–27) 17 (0–73)
IFNγ 4.6 (0–10.7) 0 (0–7.1)* 3.7 (0–10.7)
IL-5 5 (0–15) 3 (0–17) 7 (0–21)
IL-4 1.9 (0–13.6) 0.3 (0–7.4) 5.3 (0–11.4)*
Eosinophils (EG2) 1 (0–12) 2 (0–29) 11 (0–58)*
Eosinophils (MBP) 5 (0–19) 7 (2–24) 16 (3–90)*
Mast cells 15 (7–50) 19 (6–60) 26 (15–72)
Neutrophils 14 (0–50) 24 (7–45) 15 (4–64)
Macrophages 8 (0–36) 5 (0–18) 11 (0–28)
NK cells (CD56) 5.3 (0–15.6) 0.3 (0–4.8)* 2.4 (0–13.8)
Leucocytes (CD45) 53 (6–127) 40 (19–90) 56 (18–168)

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