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The radiological manifestations of severe acute respiratory syndrome (SARS) typically consist of focal unilateral or bilateral areas of hazy increased density (ground glass opacities) or airspace consolidation (fig 1A).1 In most patients the abnormalities gradually improve over several days following treatment. Approximately 20–25% of patients, however, show progressive deterioration with the development of confluent bilateral areas of consolidation.2 These patients frequently develop acute respiratory distress syndrome or have a protracted clinical course. Necroscopic examination of patients with SARS has shown features of diffuse alveolar damage. Patients with residual clinical symptoms 2 or more weeks after initial presentation often have a reticular pattern visible on the radiograph and irregular lines, architectural distortion, and traction bronchiectasis evident on the high resolution CT scan (fig 1B). These findings suggest the presence of fibrosis. Long term follow up will be required to determine the prevalence of fibrosis in patients who recover from SARS.
Characteristic radiological manifestation of SARS
Pathological findings of SARS
Long term sequelae in patients with SARS
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