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Thorax 57:837 doi:10.1136/thorax.57.9.837
  • Letters to the editor

GM-CSF therapy in pulmonary alveolar proteinosis

  1. M G de Vega1,
  2. A Sánchez-Palencia2,
  3. A Ramírez3,
  4. S Cervera3,
  5. J Aneiros4
  1. 1Respiratory Department, Hospital Virgen de las Nieves, Granada, Spain
  2. 2Chest Surgery Department, Hospital Virgen de las Nieves
  3. 3Anesthesia Department, Hospital Virgen de las Nieves
  4. 4Pathology Department, Hospital Clinico Universitario, Granada, Spain
  1. Correspondence to:
    Dr A Romero, Respiratory Department, Hospital Virgen de las Nieves, Avda de la Constitucion, Granada, Spain;
    aromeroor{at}nexo.es

    Treatment with granulocyte-macrophage colony stimulating factor (GM-CSF) has been shown to benefit a subset of patients with adult pulmonary alveolar proteinosis (PAP). A 47 year old woman with PAP, confirmed by lung biopsy, and severe physiological and symptomatic disturbances was not improved by repeated unilateral whole lung lavages. Six months after the last lavage …

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