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Thorax 2002;57:830-834 doi:10.1136/thorax.57.9.830
  • Review series

Chronic obstructive pulmonary disease c 2: Pathology and biochemistry of emphysema

  1. J C Hogg1,
  2. R M Senior2
  1. 1The University of British Columbia McDonald Research Laboratory, St Paul's Hospital, Vancouver, Canada
  2. 2Pulmonary and Critical Care Medicine, Department of Medicine, and Department of Cell Biology and Physiology, Washington University School of Medicine and Barnes-Jewish Hospital, St Louis, Missouri, USA
  1. Correspondence to:
    Professor J C Hogg, McDonald Research Laboratory, St Paul's Hospital, Vancouver, British Columbia V6Z 1Y6, Canada;
    JHogg{at}mrl.ubc.ca

    Abstract

    The pathology and pathogenesis of emphysema are reviewed, with particular reference to the proteinase-antiproteinase hypothesis.

    Footnotes

    • JCH is supported in part by the Canadian Institutes of Health Research and the NHLBI/NIH. RMS is supported in part by NHLBI/NIH and the Alan A and Edith L Wolff CharitableTrust.

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