Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations

I S Patel; T A R Seemungal; M Wilks; S J Lloyd-Owen; G C Donaldson; J A Wedzicha

doi:10.1136/thorax.57.9.759

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Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations

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	Abstract	Full	Pdf
Aug 2002	170	121	106
Sep 2002	257	520	264
Oct 2002	78	268	128
Nov 2002	34	154	61
Dec 2002	35	71	44
Jan 2003	24	79	50
Feb 2003	19	65	30
Mar 2003	13	51	15
Apr 2003	21	73	44
May 2003	15	56	25
Jun 2003	18	61	27
Jul 2003	21	87	21
Aug 2003	28	45	18
Sep 2003	15	79	27
Oct 2003	39	88	36
Nov 2003	16	49	29
Dec 2003	19	58	26
Jan 2004	22	68	41
Feb 2004	12	69	57
Mar 2004	41	93	45
Apr 2004	39	81	37
May 2004	43	121	58
Jun 2004	47	82	33
Jul 2004	36	72	38
Aug 2004	46	77	54
Sep 2004	52	115	45
Oct 2004	24	109	46
Nov 2004	19	109	61
Dec 2004	26	70	32
Jan 2005	37	67	39
Feb 2005	41	90	52
Mar 2005	31	78	64
Apr 2005	26	56	35
May 2005	26	62	44
Jun 2005	24	73	37
Jul 2005	18	58	44
Aug 2005	16	57	34
Sep 2005	23	28	34
Oct 2005	23	69	35
Nov 2005	20	67	49
Dec 2005	21	34	24
Jan 2006	18	66	34
Feb 2006	13	42	24
Mar 2006	25	72	53
Apr 2006	23	36	37
May 2006	23	43	33
Jun 2006	19	44	31
Jul 2006	26	40	28
Aug 2006	23	34	27
Sep 2006	16	54	34
Oct 2006	35	75	49
Nov 2006	38	68	48
Dec 2006	37	38	30
Jan 2007	33	53	44
Feb 2007	37	54	40
Mar 2007	22	62	35
Apr 2007	35	21	27
May 2007	37	27	16
Jun 2007	36	28	18
Jul 2007	20	24	23
Aug 2007	40	20	22
Sep 2007	38	31	22
Oct 2007	31	21	27
Nov 2007	31	23	33
Dec 2007	31	18	51
Jan 2008	39	19	20
Feb 2008	38	19	25
Mar 2008	47	34	34
Apr 2008	36	20	27
May 2008	18	17	20
Jun 2008	16	11	13
Jul 2008	20	17	18
Aug 2008	29	8	18
Sep 2008	38	17	15
Oct 2008	45	14	17
Nov 2008	27	16	17
Dec 2008	17	7	11
Jan 2009	26	9	8
Feb 2009	56	13	15
Mar 2009	47	14	19
Apr 2009	26	13	20
May 2009	49	3	14
Jun 2009	28	8	16
Jul 2009	36	14	14
Aug 2009	30	17	13
Sep 2009	52	9	13
Oct 2009	35	25	62
Nov 2009	49	9	20
Dec 2009	24	8	13
Jan 2010	27	5	13
Feb 2010	63	14	21
Mar 2010	72	18	19
Apr 2010	45	19	13
May 2010	26	9	10
Jun 2010	40	10	13
Jul 2010	29	19	15
Aug 2010	33	10	15
Sep 2010	28	8	9
Oct 2010	37	26	22
Nov 2010	83	21	16
Dec 2010	50	10	12
Jan 2011	70	23	14
Feb 2011	50	21	15
Mar 2011	49	19	22
Apr 2011	41	6	6
May 2011	40	10	14
Jun 2011	33	10	11
Jul 2011	45	9	12
Aug 2011	36	6	11
Sep 2011	52	23	23
Oct 2011	69	9	10
Nov 2011	63	31	22
Dec 2011	44	32	16
Jan 2012	51	32	19
Feb 2012	32	34	23
Mar 2012	50	30	30
Apr 2012	34	26	26
May 2012	68	45	26
Jun 2012	39	48	28
Jul 2012	66	59	32
Aug 2012	49	53	35
Sep 2012	39	72	40
Oct 2012	131	95	29
Nov 2012	72	79	48
Dec 2012	52	78	39
Jan 2013	88	90	33
Feb 2013	55	55	29
Mar 2013	74	80	37
Apr 2013	57	66	40
May 2013	57	86	34
Jun 2013	62	57	17
Jul 2013	55	58	24
Aug 2013	44	44	17
Sep 2013	47	62	14
Oct 2013	64	120	40
Nov 2013	65	92	25
Dec 2013	58	85	23
Jan 2014	41	77	24
Feb 2014	54	67	20
Mar 2014	74	83	37
Apr 2014	86	82	35
May 2014	62	74	18
Jun 2014	37	86	23
Jul 2014	47	74	19
Aug 2014	72	103	21
Sep 2014	41	65	22
Oct 2014	39	49	23
Nov 2014	80	36	33
Dec 2014	46	48	19
Jan 2015	40	43	22
Feb 2015	50	41	22
Mar 2015	75	122	36
Apr 2015	50	66	20
May 2015	45	73	16
Jun 2015	40	48	19
Jul 2015	36	43	18
Aug 2015	38	50	18
Sep 2015	87	69	29
Oct 2015	32	32	10
Nov 2015	68	65	30
Dec 2015	115	41	5
Jan 2016	52	56	16
Feb 2016	55	44	19
Mar 2016	69	52	35
Apr 2016	69	57	28
May 2016	93	92	18
Jun 2016	39	63	24
Jul 2016	58	28	19
Aug 2016	56	54	12
Sep 2016	85	47	31
Oct 2016	85	56	31
Nov 2016	88	46	17
Dec 2016	83	52	21
Jan 2017	77	63	14
Feb 2017	40	24	12
Mar 2017	37	54	68
Apr 2017	32	78	29
May 2017	28	105	30
Jun 2017	47	58	11
Jul 2017	95	66	20
Aug 2017	160	94	43
Sep 2017	201	125	44
Oct 2017	201	123	162
Nov 2017	276	180	178
Dec 2017	270	196	131
Jan 2018	316	248	147
Feb 2018	208	166	71
Mar 2018	332	240	27
Apr 2018	226	164	31
May 2018	237	179	39
Jun 2018	127	87	23
Jul 2018	85	63	19
Aug 2018	226	178	23
Sep 2018	157	111	23
Oct 2018	207	147	34
Nov 2018	159	145	19
Dec 2018	148	122	27
Jan 2019	104	87	39
Feb 2019	105	94	61
Mar 2019	89	65	20
Apr 2019	87	53	28
May 2019	93	63	21
Jun 2019	73	57	27
Jul 2019	64	51	12
Aug 2019	80	68	13
Sep 2019	82	66	8
Oct 2019	72	57	15
Nov 2019	77	51	25
Dec 2019	43	33	16
Jan 2020	64	50	12
Feb 2020	54	40	14
Mar 2020	51	35	8
Apr 2020	45	31	18
May 2020	46	29	12
Jun 2020	55	33	18
Jul 2020	49	34	20
Aug 2020	55	38	20
Sep 2020	89	49	11
Oct 2020	77	56	26
Nov 2020	44	31	17
Dec 2020	74	57	24
Jan 2021	82	58	31
Feb 2021	40	33	18
Mar 2021	55	44	24
Apr 2021	97	57	26
May 2021	62	55	35
Jun 2021	51	51	14
Jul 2021	48	48	32
Aug 2021	67	66	31
Sep 2021	90	90	35
Oct 2021	115	99	38
Nov 2021	80	47	45
Dec 2021	62	46	11
Jan 2022	55	39	14
Feb 2022	57	55	23
Mar 2022	61	55	23
Apr 2022	121	94	36
May 2022	109	93	35
Jun 2022	55	48	14
Jul 2022	56	41	13
Aug 2022	76	65	11
Sep 2022	103	87	27
Oct 2022	109	88	23
Nov 2022	95	80	14
Dec 2022	122	90	14
Jan 2023	109	96	17
Feb 2023	150	120	14
Mar 2023	110	73	15
Apr 2023	103	80	30
May 2023	68	46	25
Jun 2023	47	37	11
Jul 2023	71	51	23
Aug 2023	113	98	11
Sep 2023	126	91	24
Oct 2023	109	84	26
Nov 2023	163	144	11
Dec 2023	310	284	17
Jan 2024	101	99	49
Feb 2024	117	109	11
Mar 2024	106	78	27
Total	17006	16426	7717

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