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Thorax 57:562-563 doi:10.1136/thorax.57.6.562
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Molecular analysis of drug resistant TB

Table 1

Demographic data, site, phenotypic and genotypic resistance of the seven resistant study isolates

Resistance genotype
Isolate Age Country of birth Site of TB Drug resistance Isoniazid Rifampicin
INH=isoniazid; RIF=rifampicin; PZ=pyrazinamide. Isolates 3 and 5 had indistinguishable IS6110 types. Isolates 1 and 4 were not typable due to insufficient culture and the banding pattern of isolate 6 was uninterpretable.
1 24 Nigeria Pulmonary INH/RIF Wild type rpoB mutation
2 21 Somalia Pulmonary INH katG mutation Wild type
3 40 Zaire Pulmonary INH inhA mutation Wild type
4 17 Zaire Pulmonary INH inhA mutation Wild type
5 20 Zaire Pulmonary INH inhA mutation Wild type
6 42 UK Pulmonary INH inhA mutation Wild type
7 44 Somalia Sternum PZ Wild type Wild type

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