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Thorax 57:212-216 doi:10.1136/thorax.57.3.212
  • Original articles

Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial

Table 4

Mean (SD) QOL scores over time: baseline and final assessment (month 3)

Placebo Azithromycin
n QOL score n QOL score p value*
*Interaction of treatment effect and time. **Minimum and maximum score possible for each domain.
Dyspnoea Baseline 28 22.75 (4.86) 28 21.96 (4.68) 0.042
(range 5–35)** Final 19 25.82 (5.27) 22 28.16 (4.76)
Fatigue Baseline 30 18.87 (5.37) 30 17.17 (5.50) 0.003
(range 4–28) Final 20 18.85 (4.70) 24 21.04 (4.12)
Emotion Baseline 30 37.97 (6.84) 30 34.87 (7.63) 0.012
(range 7–49) Final 20 39.70 (5.66) 24 41.33 (7.13)
Master Baseline 30 24.37 (3.69) 30 22.70 (5.47) 0.035
(range 4–28) Final 20 25.25 (3.64) 24 25.54 (3.45)
Total Baseline 28 103.14 (14.00) 29 95.72 (18.68) 0.035
(range 20–140) Final 19 109.30 (14.78) 23 116.11 (14.67)

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