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Thorax 57:170-177 doi:10.1136/thorax.57.2.170
  • Review series

The pulmonary physician in critical care • 2: Oxygen delivery and consumption in the critically ill

Table 2

Oxygen affinities of cellular enzymes expressed as the partial pressure of oxygen in mm Hg at which the enzyme rate is half maximum (Kmo2)

Enzyme Substrate Kmo2
Glucose oxidase Glucose 57
Xanthine oxidase Hypoxanthine 50
Tryptophan oxygenase Tryptophan 37
Nitric oxide synthase l-arginine 30
Tyrosine hydroxylase Tyrosine 25
NADPH oxidase Oxygen 23
Cytochrome aa3 Oxygen 0.05

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