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Thorax 56:487-493 doi:10.1136/thorax.56.6.487
  • Original article

Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis

Table 3

Mean (SE) cytokine expression in peripheral and alveolar memory and naive lymphocytes from all sarcoidosis patients

IFNγ IL-2 TNFα IL-4 IL-5 IL-10
Blood
 Naive 7.8  (2.3) 6.9  (2.7) 4.5  (1.5) 0.9  (0.2) 0.3  (0.1) 0.9  (0.2)
 Memory 10.4 (1.9) 13.4 (3.2) 15.8 (4.2)3-150 5.2 (1.0)3-150 2.7 (1.0)3-150 3.4 (1.0)3-150
BAL fluid
 Naive 17.5 (5.9) 6.8 (3.2) 13.4 (5.5) 1.0 (0.4) 0.2 (1.0) 2.5 (0.7)
 Memory 27.2 (5.9)3-160 18.4 (6.4) 26.7 (7.5) 0.9 (0.2)3-160 0.6 (1.0) 1.6 (0.4)
  • IFNγ = interferon gamma; IL = interleukin; TNFα = tumour necrosis factor alpha.

  • 3-150 p<0.05 compared with peripheral naive lymphocytes.

  • 3-160 p<0.05 compared with peripheral memory lymphocytes.

This Article


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