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Thorax 56:406-411 doi:10.1136/thorax.56.5.406
  • Occasional review

Continuing the debate about measuring asthma in population studies

Table 3

Calculation of diagnostic statistics using recent wheeze as the index of “disease present or absent” and airway hyperresponsiveness as the index of “test positive or negative”

Disease present (recent wheeze) Disease
absent
Total
Test positive (AHR) 337  (a) 246  (b) 583
Test negative 409 (c) 2078 (d) 2487
Total 746 2324 3070
  • Sensitivity = a/(a+c) = 0.45; specificity = d/(b+d) = 0.89; positive predictive value = a/(a+b) = 0.58; negative predictive value = d/(c+d) = 0.84; positive likelihood ratio = sensitivity/ (1—specificity) = 4.1.

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