Table 1
Subjective and objective changes during observation and montelukast treatment periods
| Measurement | Run in | Change with montelukast | p value |
|---|---|---|---|
| Exercise tolerance | 5.6 (1.0 to 10.0) | 1.4 (0.0 to 3.8) | 0.008 |
| FEV1 (l) | 2.4 (0.7 to 4.2) | 0.1 (–0.2 to 0.6) | NS |
| PEFR morning (l/min) | 390 (180 to 545) | 22.8 (1.0 to 63.0) | 0.003 |
| Diurnal PEFR variability (l/min) | 34.3 (8.3 to 101.0) | –10.3 (–44.0 to 0.0) | 0.008 |
| Day to day variability in morning PEFR (l/min) | 24.0 (5.7 to 68.0) | –9.1 (–44.0 to 1.4) | 0.008 |
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Values are mean (95% confidence interval). The statistical analysis was made using Wilcoxon signed ranks test.
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FEV1 = forced expiratory volume in one second; PEFR = peak expiratory flow rate.
