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Thorax 56:186-191 doi:10.1136/thorax.56.3.186
  • Original article

Comparison of the systemic effects of fluticasone propionate and budesonide given by dry powder inhaler in healthy and asthmatic subjects

Table 2

Mean baseline values for three systemic markers of inhaled corticosteroid absorption in asthmatic and healthy subjects

Asthmatic (n=31) Healthy (n=45) Mean difference (95% CI) Ratio of geometric means (95% CI) p value
Urinary total cortisol metabolites (μg/day) 5897 8468 2571 (1237 to 3905) <0.001
Serum osteocalcin (ng/ml) 4.2 5.7 1.5 (0.87 to 2.22) <0.001
Serum cortisol2-150 (nmol/l) 449 537 1.19 (1 to 1.43) 0.05
  • 2-150 Geometric mean values.

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