Antibiotics and risk of C difficile infection
| High risk | Medium risk | Low risk |
| Cephalosporins | Ampicillin/amoxycillin | Aminoglycosides |
| Clindamycin | Co-trimoxazole | Metronidazole |
| Macrolides Tetracyclines |
Anti-pseudomonal penicillins ± β-lactamase inhibitor | |
| Quinolones | ||
| Rifampicin | ||
| Vancomycin |
-
These subdivisions may be prone to bias because of the relative frequency of use of agents and the complexity of interaction between antibiotic exposure, C difficile, and other factors.









