Table 2
Mean (SE) values of maximum pressures, spirometric parameters, serum digoxin, and pain before and after surgery in the two group of subjects
| Digoxin | Placebo | |
| Pimax (kPa) | ||
| Pre-op | 7.72 (0.86) | 9.62 (0.59) |
| Post-B | 5.52 (0.63) | 6.12 (0.41) |
| Post-A | 6.77 (0.9) | 6.38 (0.37) |
| Δ (post-A/post-B) | 1.26 (0.4)2-150 | 0.26 (0.17) |
| ΔPimax | 1.01 (95% CI 0.28 to 2.2)2-150 | |
| Pemax (kPa) | ||
| Pre-op | 10.60 (1.54) | 10.24 (1.19) |
| Post-B | 4.41 (0.35) | 5.52 (0.62) |
| Post-A | 5.70 (0.74) | 5.28 (0.40) |
| Δ (post-A/post-B) | 1.29 (0.5)2-150 | 0.24 (0.12) |
| ΔPemax | 1.05 (95% CI 0.04 to 2.4)2-150 | |
| FEV1 (% pred) | ||
| Pre-op | 111 (3.8) | 115 (6.1) |
| Post-B | 73.4 (4.3) | 77 (4.8) |
| Post-A | 75.1 (3.8) | 76.3 (4.5) |
| FVC (% pred) | ||
| Pre-op | 112 (3.5) | 107 (4.7) |
| Post-B | 70 (3.2) | 68 (3.0) |
| Post-A | 73 (5.1) | 71 (1.8) |
| FEV1/FVC (%) | ||
| Pre-op | 80 (1.3) | 83 (1.7) |
| Post-B | 77 (2.7) | 79 (2.2) |
| Post-A | 75 (3.8) | 82 (3.1) |
| VC (% pred) | ||
| Pre-op | 117 (4.7) | 108 (4.3) |
| Post-B | 75 (6.1) | 82 (3.5) |
| Post-A | 77 (5.8) | 84 (3.6) |
| Serum digoxin (ng/ml) | ||
| Post-A | 1.5 (0.67) | – |
| Pain (VAS) | ||
| Post-B | 3.3 (1.1) | 3.2 (2.1) |
| Post-A | 4.2 (2.3) | 3.7 (1.7) |
-
↵2-150 Statistically significant differences.
-
Δ(post-A/post-B) = changes in pressure after intervention in the same group; ΔPimax, ΔPemax = difference in changes in pressures after intervention between digoxin and placebo; pre-op = preoperative; post = postoperative; B = before digoxin or placebo; A = after digoxin or placebo; VAS = visual analogue scale.
