Characteristics of patients with asthma
| Mild to moderate asthma (n = 6) | Severe to life threatening asthma (n = 12) | |
| Age (years) | 41.3 (3.2) | 48.8 (5.5) |
| Sex (M/F) | 3/3 | 8/4 |
| Smoker (ex) | 1 (1) | 3 (5) |
| IgE (IU/ml) | 252.2 (91.6) | 777.3 (425.4) |
| PC20(mg/ml) | 2.03 (1.81) | 1.11 (0.53) |
| FEV1 (% pred) | 79.2 (4.5) | 63.4 (4.1)1-150 |
| FVC (% pred) | 75.1 (5.0) | 68.1 (8.5) |
| FEV1/FVC (%) | 80.0 (9.6) | 57.9 (3.8)1-150 |
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Data are expressed as mean (SE).
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PC20 = concentration of methacholine provoking a fall of 20% in FEV1 if the FEV1 ⩾75%; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity.
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↵1-150 p<0.01.









