Table 1
HLA typing data split into familial haplotypes, levels of T cell subsets, and secretion of IL-2, IL-4, and IFN-γ in four cases of familial sarcoidosis
| Case 1 | Case 2 | Case 3 | Case 4 | |
| HLA typing | ||||
| Haplotypes | A2, B7, DR12 | A2, B51, DR14 | A3, B8, DR17 | A2, B7, DR12 |
| A2, B51, DR14 | A32, B44, DR14 | A11, B7, DR15 | A11, B7, DR15 | |
| T cell subsets (×109/l) | ||||
| CD3 (NR 1.1–1.7) | 1.01 | 0.64 | 1.05 | 0.74 |
| CD4 (NR 0.7–1.1) | 0.47 | 0.44 | 0.62 | 0.29 |
| CD8 (NR 0.5–0.9) | 0.58 | 0.18 | 0.36 | 0.30 |
| Cytokines (pg/ml) | ||||
| IL-2 (NR 600–1500) | 275 | 274 | – | 63 |
| IL-4 (NR 0–35) | 426 | 13 | – | 4 |
| IFN-γ (NR 1000–20000) | 2681 | 6000 | – | 6224 |
-
IL = interleukin; IFN = interferon; NR = normal range.
