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Thorax 2000;55:343-344 doi:10.1136/thorax.55.4.343
  • Case Report

Five cases of sarcoidosis in one family: a new immunological link?

  1. J Elfordb,
  2. P Fitcha,
  3. E Kaminskic,
  4. C McGavina,
  5. I P Wellsb
  1. aDepartment of Respiratory Medicine, Derriford Hospital, Plymouth PL6 8DH, UK, bDepartment of Radiology, cDepartment of Immunology
  1. Dr C McGavin
  • Received 11 December 1997
  • Revision requested 2 March 1998
  • Revised 5 June 1998
  • Accepted 10 September 1998

Abstract

We report a family in which five members have been affected with sarcoidosis. The radiological findings of all cases are presented, together with HLA typing, T cell subset and cytokine analysis in four cases. A new HLA association in the presentation of sarcoidosis is suggested.

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