Comparison of the effects of intravenous and oral montelukast on airway function: a double blind, placebo controlled, three period, crossover study in asthmatic patients

R J Dockhorn; R A Baumgartner; J A Leff; M Noonan; K Vandormael; W Stricker; D E Weinland; T F Reiss

doi:10.1136/thorax.55.4.260

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Original article

Comparison of the effects of intravenous and oral montelukast on airway function: a double blind, placebo controlled, three period, crossover study in asthmatic patients

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	Abstract	Full	Pdf
Mar 2000	186	200	124
Apr 2000	164	223	100
May 2000	34	79	42
Jun 2000	24	30	18
Jul 2000	12	32	13
Aug 2000	15	21	15
Sep 2000	15	29	13
Oct 2000	12	23	19
Nov 2000	17	32	18
Dec 2000	9	15	8
Jan 2001	7	19	11
Feb 2001	5	32	14
Mar 2001	10	19	17
Apr 2001	11	47	26
May 2001	8	20	14
Jun 2001	2	20	7
Jul 2001	4	19	10
Aug 2001	7	30	6
Sep 2001	7	21	10
Oct 2001	6	34	5
Nov 2001	8	25	2
Dec 2001	7	12	4
Jan 2002	10	18	7
Feb 2002	9	10	8
Mar 2002	13	25	17
Apr 2002	9	19	10
May 2002	6	9	16
Jun 2002	5	7	16
Jul 2002	5	8	3
Aug 2002	5	14	11
Sep 2002	2	22	23
Oct 2002	2	17	21
Nov 2002	4	20	34
Dec 2002	7	15	16
Jan 2003	7	14	29
Feb 2003	11	26	27
Mar 2003	9	25	36
Apr 2003	13	37	28
May 2003	5	15	17
Jun 2003	3	19	30
Jul 2003	20	23	16
Aug 2003	17	24	10
Sep 2003	10	35	18
Oct 2003	41	81	23
Nov 2003	27	42	15
Dec 2003	16	18	10
Jan 2004	22	44	26
Feb 2004	19	29	23
Mar 2004	28	45	21
Apr 2004	20	46	29
May 2004	47	60	21
Jun 2004	45	51	22
Jul 2004	51	70	21
Aug 2004	58	62	17
Sep 2004	39	45	15
Oct 2004	33	41	30
Nov 2004	19	58	34
Dec 2004	15	25	15
Jan 2005	27	48	93
Feb 2005	23	40	20
Mar 2005	20	36	19
Apr 2005	7	26	20
May 2005	15	32	24
Jun 2005	17	26	29
Jul 2005	17	25	10
Aug 2005	8	24	25
Sep 2005	13	40	23
Oct 2005	19	48	32
Nov 2005	10	25	22
Dec 2005	11	34	36
Jan 2006	10	28	14
Feb 2006	5	29	15
Mar 2006	5	27	16
Apr 2006	11	23	11
May 2006	16	17	13
Jun 2006	4	18	10
Jul 2006	8	25	18
Aug 2006	16	24	16
Sep 2006	11	23	12
Oct 2006	10	22	17
Nov 2006	12	36	18
Dec 2006	6	27	13
Jan 2007	11	33	16
Feb 2007	8	25	17
Mar 2007	8	28	18
Apr 2007	11	5	9
May 2007	9	14	10
Jun 2007	20	21	12
Jul 2007	5	25	14
Aug 2007	9	6	10
Sep 2007	14	13	12
Oct 2007	17	15	21
Nov 2007	17	7	6
Dec 2007	9	13	11
Jan 2008	12	5	4
Feb 2008	12	4	8
Mar 2008	7	7	5
Apr 2008	12	7	15
May 2008	3	8	6
Jun 2008	15	4	6
Jul 2008	4	7	4
Aug 2008	14	5	5
Sep 2008	7	5	6
Oct 2008	9	1	3
Nov 2008	9	4	5
Dec 2008	7	5	7
Jan 2009	6	1	1
Feb 2009	11	6	7
Mar 2009	8	2	0
Apr 2009	10	8	12
May 2009	6	3	4
Jun 2009	1	2	2
Jul 2009	2	0	4
Aug 2009	10	6	4
Sep 2009	10	3	4
Oct 2009	9	6	0
Nov 2009	10	12	9
Dec 2009	4	3	2
Jan 2010	5	4	5
Feb 2010	5	2	4
Mar 2010	10	3	6
Apr 2010	14	11	10
May 2010	7	7	5
Jun 2010	14	16	7
Jul 2010	11	6	10
Aug 2010	6	5	4
Sep 2010	22	4	4
Oct 2010	15	2	5
Nov 2010	8	3	5
Dec 2010	5	4	5
Jan 2011	8	3	5
Feb 2011	9	3	8
Mar 2011	15	9	10
Apr 2011	4	2	2
May 2011	10	6	5
Jun 2011	12	4	6
Jul 2011	15	0	3
Aug 2011	14	5	5
Sep 2011	7	0	0
Oct 2011	18	6	2
Nov 2011	15	14	11
Dec 2011	8	11	6
Jan 2012	18	22	14
Feb 2012	26	12	14
Mar 2012	14	14	15
Apr 2012	13	5	12
May 2012	13	11	7
Jun 2012	20	8	15
Jul 2012	32	17	12
Aug 2012	15	12	10
Sep 2012	8	11	9
Oct 2012	32	13	10
Nov 2012	20	26	12
Dec 2012	14	14	14
Jan 2013	24	17	6
Feb 2013	20	9	9
Mar 2013	25	17	11
Apr 2013	19	20	6
May 2013	22	21	14
Jun 2013	14	17	15
Jul 2013	8	10	9
Aug 2013	13	11	8
Sep 2013	11	21	10
Oct 2013	19	19	9
Nov 2013	28	12	7
Dec 2013	15	9	10
Jan 2014	15	12	5
Feb 2014	12	17	4
Mar 2014	18	15	4
Apr 2014	22	16	13
May 2014	15	16	13
Jun 2014	13	12	24
Jul 2014	19	12	7
Aug 2014	11	9	6
Sep 2014	10	12	7
Oct 2014	5	1	4
Nov 2014	10	6	4
Dec 2014	4	2	3
Jan 2015	8	6	5
Feb 2015	6	8	6
Mar 2015	13	22	1
Apr 2015	14	9	2
May 2015	12	9	3
Jun 2015	10	7	4
Jul 2015	9	23	11
Aug 2015	8	10	3
Sep 2015	17	7	6
Oct 2015	10	5	0
Nov 2015	8	5	3
Dec 2015	22	13	7
Jan 2016	14	5	4
Feb 2016	6	13	3
Mar 2016	8	8	9
Apr 2016	5	4	5
May 2016	3	9	6
Jun 2016	10	4	5
Jul 2016	20	8	6
Aug 2016	8	3	2
Sep 2016	17	14	9
Oct 2016	21	12	7
Nov 2016	24	9	9
Dec 2016	18	10	1
Jan 2017	25	14	6
Feb 2017	5	6	2
Mar 2017	2	18	0
Apr 2017	5	19	1
May 2017	2	11	3
Jun 2017	4	8	3
Jul 2017	16	12	5
Aug 2017	17	13	3
Sep 2017	43	31	0
Oct 2017	29	23	3
Nov 2017	25	21	1
Dec 2017	41	39	1
Jan 2018	25	19	4
Feb 2018	21	15	5
Mar 2018	27	19	9
Apr 2018	17	11	5
May 2018	17	15	4
Jun 2018	23	15	2
Jul 2018	19	15	3
Aug 2018	34	20	2
Sep 2018	19	17	8
Oct 2018	30	20	6
Nov 2018	17	13	3
Dec 2018	27	25	1
Jan 2019	17	13	1
Feb 2019	34	26	1
Mar 2019	11	11	6
Apr 2019	24	23	4
May 2019	35	33	3
Jun 2019	14	15	11
Jul 2019	13	13	7
Aug 2019	25	19	4
Sep 2019	17	17	3
Oct 2019	16	16	9
Nov 2019	25	21	3
Dec 2019	31	28	3
Jan 2020	20	20	2
Feb 2020	9	9	3
Mar 2020	21	9	9
Apr 2020	14	12	4
May 2020	13	7	6
Jun 2020	8	8	1
Jul 2020	10	7	3
Aug 2020	13	9	13
Sep 2020	24	18	6
Oct 2020	21	19	10
Nov 2020	15	13	8
Dec 2020	12	10	1
Jan 2021	15	7	11
Feb 2021	10	10	3
Mar 2021	10	8	4
Apr 2021	7	7	5
May 2021	11	5	4
Jun 2021	15	15	4
Jul 2021	7	7	1
Aug 2021	11	12	6
Sep 2021	6	6	9
Oct 2021	19	17	17
Nov 2021	8	4	12
Dec 2021	12	8	1
Jan 2022	12	10	5
Feb 2022	9	7	3
Mar 2022	24	18	4
Apr 2022	21	17	1
May 2022	24	24	10
Jun 2022	27	25	5
Jul 2022	17	18	5
Aug 2022	27	24	8
Sep 2022	22	20	7
Oct 2022	45	42	14
Nov 2022	18	14	5
Dec 2022	12	12	2
Jan 2023	12	8	5
Feb 2023	32	29	3
Mar 2023	7	4	3
Apr 2023	15	4	5
May 2023	15	10	11
Jun 2023	10	6	4
Jul 2023	6	6	5
Aug 2023	8	8	4
Sep 2023	12	12	10
Oct 2023	7	5	1
Nov 2023	7	7	2
Dec 2023	43	30	7
Jan 2024	13	13	5
Feb 2024	8	8	3
Mar 2024	5	3	46
Total	4525	5239	3079

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