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Thorax 55:1046-1051 doi:10.1136/thorax.55.12.1046
  • Original article

Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy

Table 1

Characteristics of subjects in the OSA group and control group 2

OSA (n=21) Control group 2 (n=18) p value
Sex (M/F) 17/4 12/6
Age (years) 54 (2) 61 (2) <0.05
BMI (kg/m2) 30.9 (1.1) 25.5 (1.1) <0.05
AHI (n/hour) 37 (4)
Sao 2<90% (% of TST) 23.9 (5.4) 1.2 (2.0)
Mean Sao 2 (%) 91.8 (0.7) 94.5 (1.4)
Minimum Sao 2(%) 66.1 (2.9) 84.3 (2.5)
Arterial hypertension 12 (57%) 7 (39%) <0.05
Coronary artery disease 1 (5%) 2 (11%) NS
Cerebrovascular disease 2 (10%) 3 (17%) NS
Diabetes mellitus 1 (5%) 3 (17%) NS
Chronic renal failure
Hypercholesterolaemia 7 (33%) 5 (28%) NS
Smoking 8 (38%) 8 (44%) NS
ACE inhibitors 4 (19%) 5 (28%) NS
  • Data are given as mean (SE) or as total numbers.

  • BMI = body mass index; AHI = apnoea-hypopnoea index; Sao 2 = nocturnal oxygen saturation; TST = total sleep time; NS = not significant.

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