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Thorax 55:1023-1027 doi:10.1136/thorax.55.12.1023
  • Original article

Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families

Table 4

Influence of known risk factors on likelihood of transmission of the IL8–251A allele

Risk factor n T NT %T (95% CI) p value
All infants 83 69 43 62 (53 to 71) 0.014
Infants with no siblings 26 26 10 72 (58 to 87) 0.008
Infants with no siblings and excluding those with prematurity 20 22  7 76 (60 to 91) 0.005
Infants with no siblings and excluding those with prematurity and those with cardiac disease 18 21  6 78 (62 to 93) 0.004
  • n = number of informative probands; T = transmitted; NT = non-transmitted; %T = percentage of –215A alleles transmitted.

  • The p values, based on Pearson's test statistic, reflect the significance of the deviation of the % transmission from the expected 50%.

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