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Thorax 55:819-825 doi:10.1136/thorax.55.10.819
  • Original article

Incidence and causes of non-invasive mechanical ventilation failure after initial success

Table 2

Number and type of complications on admission and during the hospital stay in groups 1 (successfully treated) and 2 (“late failures”). Note that pneumonia and COPD exacerbations were considered causes of acute respiratory failure necessitating mechanical ventilation

On admission During hospital stay
Complications Group 1 (n=106) Group 2 (n=31) Group 1 (n=106) Group 2
(n=31)
Pneumonia 0 4 (12.9%)2-150
Cardiac impairment 22 (20.7%) 7 (22.5%) 8 (6.1%) 5 (16.1%)
Acute renal failure 9 (8.4%) 3 (9.6%) 1 (0.9%) 0
Metabolic complications 3 (2.8%) 7 (22.5%)2-151 1 (0.9%) 2 (6.4%)
Gastrointestinal complications 4 (3.7%) 1 (3.2%) 0 2 (6.4%)
Pulmonary embolism 0 3 (2.8%) 1 (3.2%)
COPD exacerbation 0 13 (41.9%)
Coma 8 (7.5%) 1 (3.2%) 0 3 (9.6%)
Shock 0 1 (3.2%) 0 1 (3.2%)
Sepsis 1 (0.9%) 3 (9.6%) 0 1 (3.2%)
DIC 0 1 (3.2%) 0 0
  • 2-150 Nosocomial pneumonia.

  • 2-151 p = 0.034, metabolic complications on admission, group 1 versus group 2.

  • DIC = disseminated intravascular coagulation.

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