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Case report
Lymphoid interstitial pneumonitis associated with common variable hypogammaglobulinaemia treated with cyclosporin A
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  1. Christopher W H Daviesa,
  2. Mark C Junipera,
  3. Winifred Grayc,
  4. Fergus V Gleesonb,
  5. Helen M Chapeld,
  6. Robert J O Daviesa
  1. aOsler Chest Unit, Churchill Hospital, Oxford Radcliffe Trust, Oxford OX3 7LJ, UK, bDepartment of Radiology, cDepartment of Cellular Pathology, John Radcliffe Hospital, Oxford Radcliffe Trust, Oxford OX3 9DU, UK, dDepartment of Immunology
  1. Dr CWH Davies

Abstract

Lymphoid interstitial pneumonitis (LIP) is a rare clinicopathological entity that may be associated with common variable immune deficiency (CVID) and may lead to respiratory failure and death. Some patients may respond to prolonged corticosteroid treatment. We hypothesised that, in view of the predominant T cell nature of LIP, cyclosporin A would be a more appropriate choice of immunosuppressive agent and report the first case of its successful use in a woman with LIP associated with CVID.

  • lymphoid interstitial pneumonitis
  • common variable immune deficiency
  • cyclosporin A

https://doi.org/10.1136/thorax.55.1.88

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