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Thorax 54:278-281 doi:10.1136/thx.54.3.278
  • Case Report

Clinical presentation of exclusive cystic fibrosis lung disease

Table 1

Electrophysiological results for the study patient. Mean (SD) values for a control group and a group of patients with CF are given for comparison

Control
group
Study patient CF group
Nasal potential difference (mV) n = 25 n = 23
 baseline and ΔPD after addition of:
  baseline −24 (11) −52 −45 (10)
  amiloride +10 (6) +21 +21 (9)
  Cl free solution −15 (10) −3 −1 (5)
  isoprenaline −8 (4) −4 −2 (3)
  ATP −1 (3) 0 −1 (3)
Intestinal current measurement (μA/cm2) n = 50 n = 51
 ΔIscafter addition of:
  amiloride −8.7 (11) −4.9 −8.7 (11)
  carbachol 38.5 (23) 45.5 −5.3 (10)
  histamine (after DIDS incubation) 33.0 (26) 19.4 −5.0 (10)

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