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Thorax 1998;53:809-811 doi:10.1136/thx.53.9.809
  • Case Report

Serum KL-6 level as a monitoring marker in a patient with pulmonary alveolar proteinosis

  1. Masamitsu Nakajimaa,
  2. Toshiaki Manabeb,
  3. Yoshihito Nikia,
  4. Toshiharu Matsushimaa
  1. aDivision of Respiratory Diseases, Department of Internal Medicine, bDepartment of Pathology, cKawasaki Medical School, 577 Matsushima, Kurashiki 701–0192, Japan
  1. Dr M Nakajima.
  • Received 13 August 1996
  • Revision requested 2 April 1997
  • Revised 7 May 1997
  • Accepted 30 May 1997

Abstract

A raised serum level of KL-6 is known to exist in active pulmonary fibrosis and KL-6 may be produced and secreted by type II pneumocytes. A case is described of pulmonary alveolar proteinosis with high serum KL-6 levels. The serum KL-6 level decreased after whole lung washing and correlated with symptoms, opacities on the chest radiograph, and arterial blood gas measurements. The serum KL-6 level may represent a useful marker for pulmonary alveolar proteinosis.

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