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Thorax 1998;53:323-325 doi:10.1136/thx.53.4.323
  • Case Report

Recurrence of recipient Langerhans’ cell histiocytosis following bilateral lung transplantation

  1. S B Habiba,
  2. J Congletonb,
  3. D Carrb,
  4. J Partridgea,
  5. B Corrinb,c,
  6. D M Geddesb,
  7. N Bannera,c,
  8. M Yacouba,c,
  9. M Burkea
  1. aTransplant Unit, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK, bRoyal Brompton Hospital, Sydney Street, London SW3 6NP, UK, cNational Heart and Lung Institute of Imperial College of Science Technology and Medicine, University of London, Dovehouse Street, London SW3 6LY, UK
  1. Dr M Burke, Department of Pathology, Harefield Hospital, Middlesex UB9 6JH, UK.
  • Received 23 July 1997
  • Revision requested 16 October 1997
  • Revised 4 November 1997
  • Accepted 20 November 1997

Abstract

Langerhans’ cell histiocytosis may cause irreversible respiratory failure due to progressive destruction of lung parenchyma and widespread cystic change. Transplantation offers a therapeutic option. A case is described of recurrence of Langerhans’ cell histiocytosis which was associated with deterioration in lung function four years following bilateral lung transplantation. Patients transplanted for Langerhans’ cell histiocytosis should be followed up with this complication in mind.

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