Table 2
Slopes of FEV1 (% predicted per year) seen in the two years before and the two years after the prescription of rhDNase by age group
| Age group (years) | N | Before rhDNase | After rhDNase | p value |
|---|---|---|---|---|
| <10 | 26 | 2.82 | −1.8 | 0.0001 |
| 10–20 | 81 | −0.25 | −3.09 | 0.0001 |
| 20–30 | 53 | −0.44 | −3.73 | 0.0002 |
| >30 | 30 | −1.29 | −1.56 | 0.78 |
-
p values are for the significance of the change in slope from the pre-therapy period to the therapy period.
