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Thorax 53:933-938 doi:10.1136/thx.53.11.933
  • Original article

Repeatability of lung function tests during methacholine challenge in wheezy infants

Table 1

Mean (SD) age, anthropometric data, and lung function test values

Infants retested (n=81) Infants not retested (n=21)
Age (months)  15.6 (6.8) (7.2–26.0)  14.2 (4.9) (6.1–21.3)
Height (cm)  78.6 (6.9) (62.3–100.1)  77.0 (5.0) (63.2–98.0)
Weight (kg)  10.4 (1.8) (6.1–17.3)  10.1 (1.6) (6.2–15.2)
First test (T1) Second test (T2)
V˙maxfrc (ml/s) 233 (108) 245 (110) 221 (112)
CV % forV˙maxfrc   8.3 (3.2)   8.4 (4.9)   9.2 (5.1)
V˙maxfrc (% pred)  66.5 (29.8)  69.4 (31.2)  63.1 (32.0)
PD15Ptco 2(μg) 233 232 223
PD30V˙maxfrc(μg) 213 294 247
  • Two consecutive tests, one month apart, were performed in 81 of the 102 infants initially included.

  • V˙maxfrc = maximal flow at functional residual capacity ; CV = coefficient of variation ; PD15Ptco 2 = mean provocative methacholine dose for Ptco 2 (geometric mean); PD30V˙maxfrc = mean provocative methacholine dose for V˙maxfrc (geometric mean).

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