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Anti-interleukin 5 strategies as a potential treatment for asthma.
  1. A D Singh,
  2. C J Sanderson
  1. Department of Clinical Immunology, Liverpool Hospital, Sydney, NSW, Australia.

    Abstract

    A paradigm shift, championed largely by cellular immunologists, has redefined asthma as an immune mediated phenomenon characterised by an interleukin 5 (IL-5) driven eosinophilic bronchitis. This change in emphasis has provoked intense interest in the possibility that inhibitors of IL-5 production, or antagonists of its activity, will provide a new generation of anti-asthma drugs.

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