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Aspergillus laryngotracheobronchitis presenting as stridor in a patient with peripheral T cell lymphoma.
  1. P. H. Kuo,
  2. L. N. Lee,
  3. P. C. Yang,
  4. Y. C. Chen,
  5. K. T. Luh
  1. Department of Internal Medicine, National Taiwan University Hospital, Taipei.

    Abstract

    Invasive aspergillosis is a serious opportunistic infection in immunocompromised patients. The case history is described of a 44 year old patient with peripheral T cell lymphoma who developed hoarseness and stridor after chemotherapy. Aspergillus fumigatus was isolated repeatedly from the sputum. Bronchoscopic examination showed symmetrical creamy-white exophytic lesions involving both vocal cords and the supraglottic area. There was diffuse tracheobronchitis with multiple raised cream-coloured plaques in the trachea which histologically consisted of numerous septate branching hyphae consistent with Aspergillus species. The lesions responded to systemic treatment with amphotericin B.

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