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Thorax 1988;43:727-728 doi:10.1136/thx.43.9.727
  • Research Article

Morning-evening changes in airway responsiveness to methacholine in normal and asthmatic subjects: analysis using partial flow-volume curves.

  1. R W Heaton,
  2. M K Gillett,
  3. P D Snashall
  1. Department of Medicine, Charing Cross and Westminster Medical School, London.

      Abstract

      In eight normal and eight asthmatic subjects airway responsiveness to methacholine was measured by means of partial flow-volume loops at 0800 and 1800 hours on the same day. Airway responsiveness was lower in the evening in both normal and asthmatic subjects.

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