Highly purified species-specific grass pollen antigens were used for inhalation bronchial challenge in 12 patients with atopic asthma. This was found to result in reproducible experimental asthma. Lodoxamide tromethamine was administered by inhalation in two different doses, 0.01 mg and 0.1 mg, to each patient, in double-blind, random, placebo-controlled manner, 15 minutes before pollen inhalation. It was found to have a significant protective action at both doses (p less than 0.05), but it produced troublesome side effects at the higher dose of 0.1 mg.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.