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A critical investigation into the antibiotic sterilization of heart valve homografts
  1. Pamela M. Waterworth,
  2. Eunice Lockey,
  3. E. M. Berry,
  4. Helen M. Pearce
  1. Departments of Microbiology, University College Hospital, London
  2. National Heart Hospital, London

    Abstract

    Waterworth, Pamela M., Lockey, Eunice, Berry, E. M., and Pearce, Helen M. (1974).Thorax, 29, 432-436. A critical investigation into the antibiotic sterilization of heart valve homografts. Sterility tests of homograft heart valves sterilized by antibiotics were found to be invalidated by carry-over of the antibiotics. A method was devised to test the efficacy of different antibiotic mixtures using membrane filters. Fifty-five organisms, including 13 species, were tested, and sterility was achieved with only 35.

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