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An economical method of comparing inhaled bronchodilators in reversible diffuse airways obstruction
  1. S. Lal,
  2. C. H. Dash,
  3. M. D. Gribben
  1. General Hospital, Bury
  2. Lancs and Clinical Research Unit, Glaxo Laboratories Ltd., Greenford, Middlesex

    With special reference to a β-2 stimulant—salmefamol

    Abstract

    Lal, S., Dash, C. H., and Gribben M. D. (1974).Thorax, 29, 317-322. An economical method of comparing inhaled bronchodilators in reversible diffuse airways obstruction: with special reference to a β-2 stimulant—salmefamol. A method is described for comparing the bronchodilator effect of a large number of drugs. It involves self-recording of peak expiratory flow rate by patients at home. From the experience gained, the method was used to compare isoprenaline, orciprenaline, terbutaline, salbutamol, and salmefamol with an inert pressurized aerosol. The results of the comparison show that the method is simple and practical and that salmefamol would seem to have a more prolonged bronchodilator effect than the other drugs tested.

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